SUBCLASS AND AVIDITY OF CIRCUMSPOROZOITE PROTEIN SPECIFIC ANTIBODIES ASSOCIATE WITH PROTECTION STATUS AGAINST MALARIA INFECTION

Abstract RTS,S/AS01 is an advanced pre-erythrocytic malaria vaccine candidate with demonstrated vaccine efficacy up to 86.7% in controlled human malaria infection (CHMI) studies; however, reproducible immune correlates of protection (CoP) are elusive.To identify candidates of humoral correlates of vaccine mediated protection, we measured antibody m

The adsorption behaviors of CO and H2 to FeO onto CaO surfaces have been studied using the density functional theory (DFT) to determine the reactions of FeO by CO and H2.The adsorption mechanisms of FeO clusters on weight the CaO(100) and CaO(110) surfaces were calculated first.The structure of the Ca(110) surface renders it highly chemically react